Propylene Glycol is FDA-approved for numerous purposes, including use in theatrical smoke machines, as a solvent for food colorings and as an additive in and medicine and food.
The Select Committee has weighed the available information and concludes that there is no evidence in the available information on propylene glycol and propylene glycol monostearate that demonstrates, or suggests reason to suspect, a hazard to the public when they are used at levels that are now current or that might reasonably be expected in future. (Source: FDA)
Propylene Glycol is a solvent for several water-insoluble drugs intended for parenteral administration; an ingredient of hydrophilic ointment; a viscous organic solvent frequently used in pharmaceutical preparations to dissolve drug substances with limited aqueous solubility; used in part for preparing injectable solutions of diazepam, phenytoin, pentobarbital, and other drugs. (Source: Farlex Partner Medical Dictionary 2012)